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However, a more detailed assessment of the morphology of the cell death revealed no evidence for the characteristics of apoptosis such as cell shrinkage, chromatin condensation, and the biochemical hallmark of caspase activation [42]

Elife 6 , e30498 (2017)

Conclusions In summary, this study demonstrates the first evidence that exogenous GABA mitigates TS-like behavior in TS model rats by modulating harmful intestinal flora and striatal GABA-glutamate metabolism, central inflammatory state, and directly enhancing neuroprotective metabolites

pneumoniae lacks the capacity for endogenous GSH synthesis